Endocrine Abstracts

Paragangliomas and Pheochromocytomas are tumors originated from chromaffin cells (Pheochromocytomas (PHEO): adrenal glands; Paragangliomas (PGL):paravertebral thoracic, abdominal, and/or pelvic sympathetic ganglia, and glossopharyngeal and vagal neck and skull base parasympathetic ganglia). Catecholamine hypersecretion predominates in PHEO, while PGL are oligosymptomatic with compression-related symptoms. The authors report the case of a 33-year-old male with an incidental ret...

A 40-year-old transfemale, regularly treated with oral estradiol (2 mg per day) and CPA (100 mg per day) for the last 15 years, presented with two asymptomatic intracranial lesions on compatible with meningiomas. Gender dysphoria since the age of 14, begins treatment in 2006. Paranoid schizophrenia at age 17. She referred to occasional headaches, without neurological defect. In the year 2013, a magnetic resonance imaging (MRI) scan revealed an expansive lesion over the sphenoi...

Steroids are still widely prescribed in pituitary trans-sphenoidal surgery (TSA). Pituitary-adrenal/thyroid/gonadal functions were prospectively evaluated in 72 consecutive NFPA pts (20–87 years, 37 M) before and after endoscopic-TSA (E-TSA) (63 at first operation, 9 at re-operation). All had macroadenoma with suprasellar extension: impinging optic chiasma in 28, extending into cavernous sinus (CS) in 23, giant in 12. Hydrocortisone was infused peri-operatively only in pt...

Hurthle cell carcinoma (HCC) represents about 5% of differentiated thyroid carcinomas. When Hurtle cell represents more than 75% of cells population, the lesion can be considered a Hurthle cell tumor (HCT); it can be classify as malignant when capsular or vascular invasion is reported or if there is a perithyroid infiltration or distant metastases occur. Aim of this study was to present our own experience on the clinical and pathological features of patients (pts) affected by ...

Merkel cell cancer, is a very rare, malignant, neuroendocrine tumour. of the skin The cause is not known. Is and often aggressive malignancy with high tendency for local recurrence, lymph node involvement and distant metastasis and a poor prognosis and rapid progression. The Merkel cell is located in or near the basal layer of the epidermis and is closely associated with terminal axons. The aims in this study we report four cases of Merkel cell tumor of the skin(1 primary and ...

Introduction: Many people suffered diverse diseases associated to central obesity. Actually the most frequent tool to estimate the abdominal fat is waist perimeter. In the past and the DXA software was adapted to measure fat content in abdominal region but the visceral and subcutaneous fat couldn’t be differentiated.Objective: Evaluate all tools available and establish the most sensible to discriminate the patients whose had risk to suffer metabolic...

Introduction: Graves’ disease is the leading cause of hyperthyroidism in the adult population. Antithyroid drugs (ATD) are the first choice worldwide, however, after an initial treatment course of 18-24 months, almost 40-50% will relapse. In these cases, current guidelines suggest a second course or prolonged use of ATD as an option. Recently, the study of quality of life (QOL) has obtained great importance, since the QOL in hyperthyroid patients is very affected. However...

Introduction: Correct titration of basal insulin is one of the most important conditions allowing Type 2 Diabetes Mellitus patients to reach correct and personalised fasting plasma glucose. The persistence of the pandemic, together with the persistence of the SARS-CoV2 virus made titration process more complex, and pushed the Lombardy diabetologists to develop solutions which could be handled by the patient independently, or with the remote online assistance of diabetes team.<...

Background: Hypothyroidism is one of the most frequent conditions in endocrinology. Despite of that fact, indications for treatment differ among specialists in Spain.Aims: To identify attitudes of Spanish endocrinologists in the use of levothyroxine (LT4) therapy and the management of hypothyroidism.Methods: The members of the Sociedad Española de Endocrinología y Nutrición (Spanish Society of Endocrinology ...

Background: RhGH treatment in adults with childhood onset growth hormone deficiency (COGHD) affect bone metabolism over time according to gender and age. A long-term study of bone mass density (BMD) in young-middle age hypopituitary patients with COGHD may better highlight possible benefits of therapy and improve clinical follow up.Methods: We enrolled 40 adults (age range during follow-up: 16.8–36 years, F: 38%) with COGHD with at least 20 years o...